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The name Bono can refer to:
- Bono (born Paul David Hewson), Irish musician, activist, and lead singer for the band U2.
- Sonny Bono, American record producer, singer, actor, and politician
- Cher, otherwise known as Cher Bono, first wife and musical partner of Sonny Bono.
- Chaz Bono (born Chastity Bono), activist, writer, actor, musician and son of Sonny Bono and Cher
- Edward de Bono, Maltese-British physician, writer, and consultant